What are they for?

The best prenatal multivitamins contain numerous important vitamins, minerals, and other components that are either essential to fetal growth and development, or that can benefit overall health of both mother and fetus. They are taken between four and six months before planning to conceive and throughout pregnancy.

The United Nations World Health Organization recommends prenatal supplementation to prevent a range of birth defects and to preserve maternal health throughout pregnancy (1). According to the World Health Organization, the nutrients that are most important to supplement before and during pregnancy include iron, folic acid; the former is to prevent anemia as blood volume increases, and the latter is to prevent neural tube defects (2, 3).

Other specific nutrients and components are beneficial for specific developmental milestones in children, including Vitamin A, Calcium, and Vitamin D (4, 5).

Research-Based Benefits

Some of the most important benefits of taking prenatal vitamins include:

  • Reduces risk of preterm birth (6)
  • Reduces risk of anemia (6)
  • Reduces the risk of neural tube defects in babies, like spina bifida (7)
  • Improves child bone mass (5)
  • Promotes fetus brain health (8)
  • Promotes maternal and fetus thyroid health (8)
  • Reduces risk of birth defects (9)
  • Ginger and B6 in supplements can help reduce morning sickness and nausea (10)

 

Recommended for:*

  • Women who are at risk of unplanned pregnancy
  • Women who are planning to become pregnant
  • Women who are pregnant

*These are general recommendations and do not replace medical prescriptions or recommendations.

 

Research Summary:

Outcome

Findings

Dose

Study Reference

Decreased risk for several congenital anomalies.

Maternal consumption of folic acid-containing prenatal multivitamins is associated with decreased risk for several congenital anomalies, not only neural tube defects

Systematic review of several studies.

(11)

Reduction in risk of preterm delivery.

Reduction in risk of infant low birth weight and very low birth weight.

In low income, urban women, use of prenatal multivitamin/mineral supplements may have the potential to diminish infant morbidity and mortality.

Prenatal vitamin supplementation daily during 1st and 2nd trimesters

(12)

Decreased risk for pediatric brain tumors, neuroblastoma, and leukemia

There was an apparent protective effect for leukemia (odds ratio (OR)=0.61, 95% confidence interval (CI)=0.50–0.74), pediatric brain tumors (OR=0.73, 95% CI=0.60–0.88) and neuroblastoma (OR=0.53, 95% CI=0.42–0.68).

Systematic review of 61 studies.

(13)

Similar levels of iron absorption in low-iron-containing supplement

The absorption of iron from a low-iron-containing supplement was similar to that from a supplement with almost twice the amount of iron, due possibly to the exclusion of calcium in the LI product.

Not provided

(14)

Multiple micronutrients did not increase weight gain during pregnancy when compared to iron supplements

Compared to iron supplements, MM supplements did not increase weight gain during pregnancy after adjusting for baseline differences in BMI

Multiple micronutrient or Iron-only supplements for 6 days a week.

(15)

Lower fat mass increase in first 5 months of life

Increased multivitamin use in the pre‐conception and prenatal periods was associated with a slower rate of growth in offspring percent fat mass in the first 5 months of life.

Supplementation in the year before birth.

(16)

Reduction in risk of genitourinary tract anomalies.

Maternal prenatal multivitamins may reduce the risk of congenital genitourinary tract anomalies, not only during the first 8 weeks of gestation but also later in pregnancy, in developing countries.

General prenatal use. 

(17)

Reduced risk of preterm birth.

These results suggest that, compared with nonusers, women who take multivitamin supplements prior to conception may have a reduced risk of preterm birth.

Pre-pregnancy multivitamin use.

(18)

 

Stride Prenatal Vitamins – What’s in Them?

Our prenatal multivitamin contains 29 vitamins, mineral, and herbs to support fertility, to support healthy fetus growth and development, and to promote the mother’s health.

Our formula contains the following:

Component

%DV or dose

Vitamin A

50%

Vitamin C

167%

Vitamin D

100%

Vitamin E

100%

Vitamin K2

*

Vitamin B-1

588%

Riboflavin

500%

Niacin

100%

Vitamin B-6

600%

Calcium Folinate

100%

Vitamin B-12

313%

Biotin

100%

Vitamin B-5

150%

Calcium

15%

Iron

167%

Iodine

100%

Magnesium

22%

Zinc

100%

Selenium

100 mcg

Copper

2 mg

Manganese

2 mg

Chromium

120 mcg

Molybdenum

75 mcg

Potassium

10 mg

Choline

10 mg

Inositol

10 mg

Boron

1 mg

Ginger

50 mg

Red Raspberry Leaf

50 mg

 

 

 

References

  1. https://www.who.int/nutrition/publications/pregnant/en/
  2. https://www.who.int/nutrition/publications/micronutrients/WIFS-anaemia-prevention-women-adolescent-girls/en/
  3. https://www.who.int/nutrition/publications/guidelines/optimalserum_rbc_womenrep_tubedefects/en/
  4. http://www.who.int/nutrition/publications/guidelines/antenatalcare-pregnancy-positive-experience/en/
  5. https://www.sciencedirect.com/science/article/pii/S0140673606679221
  6. https://www.sciencedirect.com/science/article/pii/S0899900710000031
  7. https://jamanetwork.com/journals/jama/article-abstract/379576
  8. https://academic.oup.com/ajcn/article/89/2/668S/4596762
  9. https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/folate-vitamin-b12-and-homocysteine-in-relation-to-birth-defects-and-pregnancy-outcome/EA42FFF92AE246CBCDDE20C404B2AF4D
  10. https://europepmc.org/abstract/med/14649969
  11. https://www.sciencedirect.com/science/article/pii/S1701216316322277
  12. https://academic.oup.com/aje/article/146/2/134/165151
  13. https://ascpt.onlinelibrary.wiley.com/doi/abs/10.1038/sj.clpt.6100100
  14. https://www.sciencedirect.com/science/article/pii/S1701216316301530
  15. https://journals.sagepub.com/doi/abs/10.1177/156482650502600304
  16. https://onlinelibrary.wiley.com/doi/abs/10.1111/ijpo.12084
  17. https://www.sciencedirect.com/science/article/pii/S1477513111001781
  18. https://academic.oup.com/aje/article/160/9/886/86599